Household characteristics affecting allergen and fungal levels in inner-city residences: A longitudinal study. Sook Ja Cho

ISBN: 9780549402411

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NOOKstudy eTextbook

191 pages


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Household characteristics affecting allergen and fungal levels in inner-city residences: A longitudinal study.  by  Sook Ja Cho

Household characteristics affecting allergen and fungal levels in inner-city residences: A longitudinal study. by Sook Ja Cho
| NOOKstudy eTextbook | PDF, EPUB, FB2, DjVu, AUDIO, mp3, RTF | 191 pages | ISBN: 9780549402411 | 5.32 Mb

This thesis consists of three sections which address a different aspect of allergen and fungal exposure assessment in order to better understand variability of levels of three allergens (cat, cockroach, and dust mite) and culturable fungi inMoreThis thesis consists of three sections which address a different aspect of allergen and fungal exposure assessment in order to better understand variability of levels of three allergens (cat, cockroach, and dust mite) and culturable fungi in inner-city households.

The first section examines residential and seasonal factors affecting variability of three allergen and culturable total fungal levels in house dust. Sampling season was the most important source of variability for dust mite allergen and culturable total fungal concentrations within homes, while residential characteristics such as race/ethnicity, family income, and the presence of cat mainly influenced variability of cat and cockroach allergen levels.

The results suggest that a single observation of cat allergen is a good proxy for a 1-year exposure while total fungi will require repeated measurements to robustly estimate long-term exposure in residencies.-The second section characterizes seasonal variability of individual fungal concentration (CFU/g) at the genus level. The majority of fungal genera showed seasonal variability when expressed as the frequency of occurrence, fraction of total fungal concentration (%), and a concentration of individual genera (CFU/g), but the seasonal patterns varied by genus.

Seasonal variability of concentrations of fungal genera was larger than that for total fungi. The results suggest that longitudinal studies should be conducted for fungal exposure assessment at the genus or species level.-The third section assesses the predictive value of a visual home assessment tool for identification of allergen and culturable fungal levels in house dust. The variables that are commonly believed to be associated with allergen and fungal levels, such as full trash cans, dishes in sink, uncovered food, and visible mold, were not associated with dichotomized allergen and fungal levels.

In addition, no home environment characteristics associated with detectable levels of cat, cockroach, and dust mite allergens met the criteria of both high sensitivity and specificity. The results suggest that the visual inspection tool are not useful for the identification of the dichotomized allergen and fungal levels, and dust samples are required to accurately assess allergen and fungal levels in house dust.



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